Do not use SYMBICORT for patients whose asthma is adequately controlled on low or medium dose inhaled corticosteroids
Dosage
Symbicort is available in two strengths: 80 mcg/4
The dosages given are based on the following sources: Print Save Symbicort Generic name: budesonide and formoterol (inhalation) [ bue-DES-oh-nide-and-for-MOE-te-rol ] Drug class: Bronchodilator combinations Medically reviewed by Sanjai Sinha, MD
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ICS Dose Level Therapy; Low: Advair HFA 45/21 - 2 puffs 2x daily: AirDuo Respiclick 55/14 - 2 puffs 2x daily Symbicort HFA 160/4
The maximum recommended dosage is SYMBICORT 160/4
Use the lowest dose of inhaled corticosteroid (ICS) that maintains effective control of asthma and start ICS at a dose appropriate to the severity of symptoms
Close monitoring for dose-related adverse effects is needed in patients who frequently take high numbers of Symbicort as-needed inhalations
The alternatives are medium-dose inhaled glucocorticoids plus a LTRA or, in children ≥5 years of age, high-dose inhaled glucocorticoids or medium-dose inhaled glucocorticoid-LABA plus tiotropium or LTRA
5 twice daily
It is not known if SYMBICORT is safe and effective in children less than 6 years of age with asthma
Management of asthma exacerbations in primary care
For children between the age of 5 and 11 with moderate to severe asthma, the standard dose is one to two puffs twice daily, then one to two puffs every four hours, as required
COPYRIGHT 2002 Adult steroid dose Low adult steroid dose
5 twice daily
Each inhalation contains 80 or 160 micrograms (mcg) of budesonide and 4
Shake well prior to each inhalation
Symbicort should only be used in people with moderate-to-severe asthma that remains uncontrolled despite regular inhaled corticosteroids
Symbicort is indicated in adults and adolescents (12 years and older) for the regular treatment of asthma, where use of a combination (inhaled corticosteroid and long-acting β 2 adrenoceptor agonist) is appropriate: - patients not adequately controlled with inhaled corticosteroids and "as needed" inhaled short-acting β 2 adrenoceptor agonists
(based on 4 puffs / day) Inhaled corticosteroid information For children and adults, a total of 2 puffs/day gives a low dose of ICS; for adults, 4 puffs/day gives a medium dose
For adult and adolescent patients aged 12 years and more, the recommended dosage of Symbicort® 160/4
• Dose Low dose Medium dose High dose# Pressurised metered dose inhalers (pMDI) Beclometasone dipropionate # High doses (shaded boxes) should only be used after referring the patient to specialist care
Therapeutic index values >1 were seen for CIC, FP, MF and FF, with the highest value of 5
5 mcg/actuation: 2 inhalations bid
13-18 In a network meta-analysis, low- and medium-dose single ICS/formoterol maintenance and reliever aMedical Research Institute of New Zealand, Wellington, New Zealand bCapital and Coast District Health Board, therapeutic regimens including low-, medium-, and high-dose ICS/long-acting beta 2-agonist (LABA) maintenance plus INTRODUCTION
Maximum dose: 24 mcg daily
in adults and children, use a pressurized metered-dose inhaler and spacer, with a
Uses
Medscape - Asthma and COPD dosing for Symbicort, Breyna (formoterol/budesonide
Cost Precautions Overdose For professionals What is Symbicort?
Use the lowest dose of inhaled corticosteroid (ICS) that maintains effective control of
If you need
Close monitoring for dose-related adverse effects is needed in patients who frequently take high numbers of Symbicort as-needed inhalations
Severe asthma is asthma that remains uncontrolled despite treatment with a high-dose ICS combined with a LABA, LAMA, or LTRA for the past year or regular use of oral corticosteroids
Bottom Line
For children ages 12 and older, the standard dosage for asthma is two puffs of Symbicort 80 twice daily
5 mcg) q12hr Pr SYMBICORT ® TURBUHALER® not use SYMBICORT for patients whose asthma is adequately controlled on low- to medium-dose inhaled corticosteroids
SYMBICORT is for adults and children with asthma who need both an ICS and LABA medicine
SYMBICORT contains an ICS and a LABA
For patients 12 years of age and older, the dosage is 2 inhalations of SYMBICORT 80/4
5 mcg of formoterol
Control arms for comparison included 2 inhalations of budesonide HFA metered dose inhaler (MDI) 80 or
If symptoms arise between doses, use an inhaled short-acting beta 2
Recommended doses: Adults and adolescents (12 years and older): The recommended maintenance dose is 4 actuations per day, given either as 2 actuations in the morning and evening or as 4
LABA medicines, like formoterol, help
Inhaled budesonide belongs to the family of medicines known as corticosteroids (cortisone-like medicines)
Asthma Maintenance therapy Adult ≥18 yr 1-2 inhalations bd, may be increased up to max: 4 inhalations bd